B Vitamins May Help Improve Schizophrenia Symptoms

According to a study published in the Journal of the American Medical Association (JAMA), folic acid (also known as folate or vitamin B9) may help improve the negative associated schizophrenia symptoms in certain individuals.

Supplementing antipsychotic medication with folate plus vitamin B12 as an adjunctive treatment can improve negative symptoms of schizophrenia, a new study shows.

However, the randomized clinical trial also suggests that the level of treatment response is more significant in individuals with specific gene variants involved in folate metabolism.

“Our finding that folate plus vitamin B12 supplementation can improve negative symptoms opens a new potential avenue for treatment of schizophrenia. Because treatment effects differed based on which genetic variants were present in each participant, the results also support a personalized medical approach to treating schizophrenia,” study investigator Joshua Roffman, MD, said in a release. See original story

Schizophrenia is a devastating mental condition that can negatively impact quality of life for sufferer as well as those around him/her. The person who has the condition is likely to be placed on a lifetime of medication.

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